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KMID : 0381219820140010097
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Journal of RIMSK
1982 Volume.14 No. 1 p.97 ~ p.105
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Clinical Observation on Diabetes Mellitus
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Abstract
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Diabetes mellitus is a generalized, chronic metabolic disorder. And the prevalence of diabetes mellitus is progressively increasing now.
If the disease is prolonged, it is usually complicated by degenerative changes of the blood vessels, particularly in the retina, the kidney, and in the nervous system which are the major causes of morbity and mortality in diabetic patients. So the development of effective forms of treatment are needed for prevention and treatment of complications of diabetes mellitus.
A clinical status was studied on the two hundred seventy seven cases of diabetic patients who were admitted to Chung-Ang University hospital from January, 1976 to August, 1979. The results were as follows:
1. Diabetes mellitus was found in 277 cases (1.5%) among total 18,021 admitted patients. The male patients
predominated the female by the ratio of 1.4 : 1.0.
2. The highest incidence was in the 6th decade (36.5%), the 7th decade (27.8%), and the 5th decade (16. 6%) in order of frequency.
3. The probable precipitating factors of the disease were infections (19.9%), obesity (18.8%), and trauma (5.8%) in order of frequency. But in the great majority, no precipitating factors could be found (52. 3%).
4. The common symptoms at the admission were general weakness (16.9%), polydipsia (10.5%), and polyuria (9.9%) in order of frequency.
5. The ECG findings in diabetics were ST-T wave changes (19.6%), LVH(16.2%), and atrial fibrillation (3.176) in order of frequency. But in the great majority, no ECG abnormalities could be found (57.6%).
6. The abnormalities of blood chemistry in diabetics were found in cholesterol (43.3%), alkaline phosphatase (41.3%), creatinine (19.4%), BUN (36.2%), SGOT(20.2%), and SGPT(27.6%).
7. The fasting blood glucose levels on admission were between 150 and 199mg% (26.7%), 220 and 249mg% (22%), 120 and 149mg%(21.7%) of patients in order of frequency. And the postprandial two hour glucose levels before treatment were between 250 and 299mg% (39.6%),200 and 249mg% (34.7%), 300 and 349mg% (17.3%), and more than 350mg% (8.4%) in order of frequency.
8. The diabetic complications were retinopathy (21.1%), cardio-vascular complications (20.7%), and infections (15.7%) in order of frequency.
9. On the relationship between fasting blood gluose levels and response to treatment, good control could be
achieved by diet alone if fasting glucose levels were low in contrast to good control by combination treatment of diet and insulin if fasting glucose levels were high.
10. Serum insulin levels were measured in control and diabetics. The serum insulin levels were well increased after eating in control but not increased in diabetic patient after eating.
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